
Depression affects millions of people worldwide, and while many find relief through medication or psychotherapy, others struggle with treatment-resistant cases. For these patients, finding a safe and effective solution can be challenging. In recent years, TMS treatment for depression has emerged as a non-invasive therapy that offers hope when traditional methods fall short.
Transcranial Magnetic Stimulation (TMS) uses magnetic pulses to stimulate specific areas of the brain involved in mood regulation. Unlike medication, which affects the entire body, TMS works directly on targeted brain regions, making it an attractive option for patients who either do not respond to or cannot tolerate antidepressants. This article explores how TMS helps in resistant cases, its benefits, and its role alongside other therapies such as OCD therapy.
Treatment-resistant depression (TRD) refers to cases where patients do not experience significant improvement despite trying at least two different antidepressants at adequate doses. TRD can affect quality of life, relationships, and the ability to function daily.

There are several reasons why medication may not work for everyone, including:
This is where TMS can play a vital role by directly stimulating neural pathways involved in mood regulation.
During a TMS session, an electromagnetic coil is placed on the patient’s scalp. The device delivers magnetic pulses to areas of the brain associated with mood control, particularly the left prefrontal cortex. These pulses activate neurons, encouraging brain circuits to function more effectively.
TMS provides a new pathway for patients who have tried multiple antidepressants without success. Many patients report noticeable improvements in mood and functioning after completing a treatment course.
Unlike medications that may cause weight gain, fatigue, or sexual dysfunction, TMS side effects are usually mild and temporary, such as scalp discomfort or a mild headache.
Research suggests that benefits from TMS can last months or even years, particularly when patients continue follow-up care and healthy lifestyle practices.
Patients often report better sleep, improved focus, and increased motivation, which positively impacts both personal and professional life.
Depression often occurs alongside other mental health disorders, including Obsessive-Compulsive Disorder (OCD). Traditional OCD therapy, such as cognitive behavioural therapy (CBT) and medication, can be effective, but some patients continue to struggle.
TMS is also being studied for its effectiveness in treating OCD. Stimulating different brain areas can help reduce obsessive thoughts and compulsive behaviours. For patients experiencing both depression and OCD, combining TMS with standard OCD therapy may provide more comprehensive relief.
While TMS is not a replacement for therapy, it can work alongside counselling, lifestyle changes, and medication adjustments. This integrated approach ensures that both depression and co-existing conditions like OCD are managed more effectively.
Most TMS courses involve sessions five days per week for four to six weeks. Each session typically lasts 20 to 40 minutes, making it manageable for working professionals and busy individuals.
Patients remain awake and alert during treatment. Some may feel a tapping sensation on the scalp, but discomfort is usually minimal.
Improvements are often noticed gradually, with some patients reporting mood changes within two to three weeks. For others, progress may be slower but still significant by the end of the treatment course.

Regular check-ins with a mental health professional are essential to monitor progress. Some patients may benefit from maintenance TMS sessions.
Healthy habits such as regular exercise, balanced nutrition, mindfulness practices, and adequate sleep support long-term improvements in mood.
For those undergoing OCD therapy or other forms of counselling, TMS can make sessions more effective by reducing depressive symptoms that may interfere with progress.
Patients may be considered for TMS if they:
A consultation with a qualified mental health specialist will determine whether TMS is the right option.
TMS treatment for depression offers hope for patients who have struggled with resistant cases and found little relief from medication. By directly stimulating the brain areas linked to mood regulation, TMS provides a safe, effective, and non-invasive option.
When combined with ongoing therapies such as OCD therapy, lifestyle changes, and professional support, TMS can significantly improve quality of life. For individuals living with treatment-resistant depression, this approach may provide the breakthrough they need to move forward with greater confidence and stability.